3 factors interfering with quality replication of the signal of interest
Báo cáo y học: "Characteristics of HIV-infected women and factors associated with HCV seropositivity in the Republic of Georgia" doc
Ngày tải lên :
10/08/2014, 05:22
... closely tied to the IDU community The majority of HIV positive women (70%) have a documented connection to the IDU community through either their own IDU (n = 10) or a partner with IDU (n = 163) ... it is unlikely that the high prevalence of HCV in our study was solely due to the sexual exposure to the virus Evidence suggests that IDU is one of the most efficient modes of HCV transmission,[27] ... Cohort studies among persons with IDU showed that the incidence of HCV was greatest within the first year of follow-up and ranged from 16.1/100py to 41.8/100py [31-33] The same studies reported...
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Factors Affecting Audit Quality in the 2007 UK Regulatory Environment: Perceptions of Chief Financial Officers, Audit Committee Chairs and Audit Engagement Partners ppt
Ngày tải lên :
16/03/2014, 00:20
... is the latest event to raise interest globally in audit quality, the integrity of financial reporting and corporate governance The scale of the problem has also raised expectations of further ... services (APB, 2004a) The POB became responsible for the inspection of public interest audits and the publication of the results of the inspections This work is carried out by the POB’s Audit Inspection ... member of the audit committee has recent and relevant financial experience.’ The responsibilities of the audit committee include monitoring the integrity of the financial statements of the company…reviewing...
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Báo cáo khoa học: Interaction of DAPI with individual strands of trinucleotide repeats Effects on replication in vitro of the AATÆATT triplet docx
Ngày tải lên :
16/03/2014, 23:20
... limited case of six triplet sequences, the specificity of the observed effects confirms the higher selectivity of DAPI for the minor-groove of the ATT-triplet with respect to all the other individual ... produced by the ATT-template in the presence of DAPI (Fig 3, lane 4), the observation of a monophasic thermal transition is consistent with the prevalent presence of a single DNA structure in the complex, ... favourable characteristic of the TÆT minorgroove than the AÆA minor-groove, in the binding of DAPI [16] In conclusion, the main cause of the strong inhibitory effect of DAPI on DNA replication in vitro...
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Báo cáo Y học: A polymer with a backbone of 3-deoxy-D-glycero -D-galacto -non-2ulopyranosonic acid, a teichuronic acid, and a b-glucosylated ribitol teichoic acid in the cell wall of plant pathogenic Streptomyces sp. VKM Ac-2124 pdf
Ngày tải lên :
17/03/2014, 10:20
... and 69.4 Other signals of the spectrum were found at d67.9–80.4, i.e in the region of resonances of CH groups bound to one oxygen atom The region of resonances of the anomeric protons in the H NMR ... proves the position of the acetamido groups at C-2 and C-3 of this sugar The signal of the H-5 of this sugar appeared as a doublet, which suggests the absence of protons at H-6 In addition, the ... were observed in the region of resonances of the CH3CO– groups The presence of 3-deoxynonulosonic acid with the b-configuration of the glycosidic bond followed from two doublets of doublets at d2.20...
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Báo cáo khoa học: Fast set-up of doxycycline-inducible protein expression in human cell lines with a single plasmid based on Epstein– Barr virus replication and the simple tetracycline repressor ppt
Ngày tải lên :
23/03/2014, 09:21
... Addition of tetracycline or doxycycline to the culture medium turns on expression: the inducer binds to the repressor, which then dissociates from the operator From the lack of interaction of the ... proportion because of the limited capacity of the synthesis machinery, especially for membrane proteins [17] To improve the signal- to-noise ratio, we thus aimed to reduce the efficiency of translation ... that the mRNA of OCT1h was predominantly terminated upstream of the EBNA-1 binding site region With pEBTetD, the copy number of OCT1h mRNA was reduced as compared with pEBTet by a factor of nine...
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Báo cáo Y học: Inhibition of SERCA Ca2+ pumps by 2-aminoethoxydiphenyl borate (2-APB) 2-APB reduces both Ca2+ binding and phosphoryl transfer from ATP, by interfering with the pathway leading to the Ca2+-binding sites ppt
Ngày tải lên :
31/03/2014, 23:20
... absence of 2-APB the ATPase had a Vmax of 11.4 ± 0.3 UÆmg)1, with the Km for the stimulatory phase of 0.40 ± 0.03 lM, and the Km for the inhibitory phase of 0.35 ± 0.06 mM However, in the presence of ... 2-APBbinding sites within the structure of the Ca2+-ATPase using procedures and assumptions as described in Materials and methods Analysis of the interactions of 2-APB with the structure of the ATPase ... explanation for the pH-sensitivity of 2-APB inhibition would therefore be due to protonation of various amino-acid residues within the ATPase at pH Furthermore, as the rate limiting steps within the enzymes...
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báo cáo hóa học: " Replication of the association of HLA-B7 with Alzheimer''''s disease: a role for homozygosity?" pptx
Ngày tải lên :
19/06/2014, 22:20
... view of the consistency between the results of the two studies, we pooled the two datasets for further analysis of HLA-B7 and HLACw*0702 Possible interactions of HLA-B7 and HLA-Cw*0702 with other ... associations of AD with HLA-B & C alleles Tables and show the overall results for the 26 studied alleles Apart from the associations with HLA-B7 and HLA-Cw*0702 (see below), there was one other apparently ... analysis Of the 26 studied alleles, 14 had a minor allele frequency > 5% In the overall analyses of each allele, therefore, a Bonferroni correction factor of 14 was applied, except in the replication...
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báo cáo hóa học:" Quality of life and pain in premenopausal women with major depressive disorder: The POWER Study" pdf
Ngày tải lên :
20/06/2014, 15:20
... sleep quality, and impaired quality of life [12] The aims of the current study were: 1) to establish the prevalence of pain and associated symptoms in premenopausal women with MDD compared to healthy ... history of depression of approximately cumulative years and an average of four episodes of depression Of the 69 patients with MDD for whom depression scores were available, had a Ham- Page of (page ... less All subjects had had an episode of major depression within the past three years Consistent with their mild depression at the time of evaluation, UFC was within normal limits and not different...
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Báo cáo toán học: "Tilings of the sphere with right triangles II: The (1, 3, 2), (0, 2, n) subfamily" ppt
Ngày tải lên :
07/08/2014, 13:21
... Proposition If the configuration of Figure 4b appears in a tiling of the sphere with the triangle T6 , centered on the (0, 5, 1) vertex O, then the tiling contains another copy of the same configuration ... vertex The next proposition eliminates one of these possibilities Proposition If the configuration of Figure 5b appears in a tiling of the sphere with triangle T6 , then E is a (0, 5, 1) vertex Proof: ... edges Proposition If the configuration of Figure 8c appears in a tiling of the sphere with the triangle T6 , the medium edge of triangle cannot be matched the electronic journal of combinatorics 13...
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Báo cáo khoa học: "Predicting the yield of Douglas fir from site factors on better quality sites in Scotland" pot
Ngày tải lên :
08/08/2014, 19:21
... score (which is the sum of the angles to the horizon at the cardinal points of the compass) was the single most significant factor affecting productivity, explaining 32-69% of the variation in ... Scotland 2) The level of precision of the predictions for GYC from regression model are adequate for strategic modelling of wood flow In 95% of the cases, the true value for the GYC will lie within ... expected, the effect of increasing geomorphic shelter is to increase pro- ductivity Tests of the effects of qualitative soil variables in the model resulted in the addition of SITEDR The drainage...
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Báo cáo y học: "Replication of association of the D-repeat polymorphism in asporin with osteoarthristis" docx
Ngày tải lên :
09/08/2014, 08:22
... an important effect of the asporin D repeat polymorphism; this was similar to the conclusion of the authors of the UK study [3] Our conclusion was based in the analysis of the three available ... analysis includes the result used as reference, the Japanese study, in the subject of the comparison The correct probability is 1/8 = 0.125 Regarding the comment on the power of our study, we ... that it is enough to detect effects of the size observed in the Japanese study (with the exceptions mentioned in our article) In addition, the larger power of the combined European studies did...
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Báo cáo y học: "Risk factors associated with the loss of cartilage volume on weight-bearing areas in knee osteoarthritis patients assessed by quantitative magnetic resonance imaging: a longitudinal study" pot
Ngày tải lên :
09/08/2014, 10:20
... about the topographical loss of cartilage in the different subregions of the knee and the associated risk factors Moreover, the impact of the location and rate of cartilage loss on the evolution of ... time as the disease progressed The relationship between the worsening in the WOMAC scores with the loss of cartilage on the central portion of the tibial plateau is intriguing The level of significance ... evidence of OA of the affected knee on a radiograph obtained within months of the outset of the study Finally, patients had to have a minimum joint space width (JSW) of the medial compartment of between...
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Báo cáo khoa học: " Comparing two strategies of dynamic intensity modulated radiation therapy (dIMRT) with 3-dimensional conformal radiation therapy (3DCRT) in the hypofractionated treatment of high-risk prostate cancer" doc
Ngày tải lên :
09/08/2014, 10:21
... Specifically, the entire outer wall of the bladder is contoured, the rectum is contoured from the anus (at the level of the ischial tuberostities) for a length of 15 cm or to where the rectosigmoid ... distal to bifurcation of the common iliac), and external iliac vessels (to the top of the superior pubic symphysis) were outlined from L5-S1 to the top of the symphysis pubis The conformal pelvic ... transferred to the TomoTherapy planning workstation using the DICOM RT protocol The TomoTherapy station re-sampled the CT datasets in 256 × 256 voxels with the slice thickness re-sampled to the smallest...
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Báo cáo y học: " Sociodemographic and occupational risk factors associated with the development of different burnout types: the cross-sectional University of Zaragoza study" docx
Ngày tải lên :
11/08/2014, 15:22
... profile is associated with the cumulative effect over time of the characteristics of an organisation The recognition of these variables will assist the process of clinical differentiation of ... present with feelings of a lack of control over the results of their work and a lack of acknowledgement for their efforts, which finally leads them to neglect their responsibilities “Lack of control” ... associated with all of the dimensions of the definition by Maslach, Schaufeli and Leiter [2] It is, therefore, the profile of exhausted, cynical and rather ineffective workers [15-17,20,27-30] The work...
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báo cáo khoa học: " Developing the protocol for the evaluation of the health foundation''''s ''''engaging with quality initiative'''' – an emergent approach" pps
Ngày tải lên :
11/08/2014, 16:21
... objectives of the EwQI are given in Table 1, and the criteria for the selection of the projects in Table The immediate inspiration for the EwQI came from Leatherman and Sutherland's book 'The Quest ... This had the dual benefit of enabling us to clarify these requirements with The Health Foundation, and of providing us with a tool through which to discuss them with the project teams The guidance ... review In the light of the teams' lack of interest in logic models, we are using their self evaluation returns to highlight the key theories underpinning each project and explore these with them We...
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Báo cáo y học: " Analysis of a new strain of Euphorbia mosaic virus with distinct replication specificity unveils a lineage of begomoviruses with short Rep sequences in the DNA-B intergenic region" pdf
Ngày tải lên :
12/08/2014, 01:22
... observations support the hypothesis of intermolecular recombination: (1) The absence of a G-box element within the CR of the DNA-A component of EuMV-YP, that is nevertheless present in their cognate ... ~210-bp DNA segment encompassing the region of the virus replication origin and the first 44 nucleotides of the rep gene If this hypothetical scenario is accurate, then the recombination event should ... 12 of 15 Figure Potential internal promoter in the DNA-B intergenic region of EuMV Alignment of a domain of the DNA-B intergenic region of EuMV-Jal with the coat protein (CP) gene promoter of...
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Báo cáo y học: "Factors associated with mosquito pool positivity and the characterization of the West Nile viruses found within Louisiana during 2007" ppsx
Ngày tải lên :
12/08/2014, 04:20
... May 2007 shows the land cover of Louisiana Pertinent parishes are labelled with their parish names together as representative of the North American 2002 clade The between and within distances ... produced As the topologies of the E and NS3 phylogenies were the same, our tree represents a contiguous sequence of these two genes The topology tree was collapsed with a node confidence of 70% Genetic ... also interesting that there is more genetic diversity within Louisiana than without That is, the diversity when comparing between the wetlands and forests within Louisiana is greater than the...
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Báo cáo khoa học: "A farm-level study of risk factors associated with the colonization of broiler flocks with Campylobacter spp. in Iceland, 2001 – 2004" pot
Ngày tải lên :
12/08/2014, 18:22
... included the use of official or official treated water on the farm compared to the use of non-official untreated water, storing manure on the farm at any time of year, and the presence of other domestic ... (i.e the practice of shipping all flocks on the farm within the span of a few days, with all houses remaining empty for a period of time) was not a significant predictor in any of the models The ... another component of the full project) During the first eight months of sampling, caecal samples were analysed by both methods [30] Based on the results of this comparison, the Laboratory of the...
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Báo cáo khoa học: "Factors associated with the success of rabies vaccination of dogs in Sweden" doc
Ngày tải lên :
12/08/2014, 18:22
... http://www.actavetscand.com/content/53/1/22 Page of Model validation was preformed according to Hosmer and Lemeshow [7] The fit of the model was evaluated with the Hosmer-Lemeshow goodness -of- fit test with the data partitioned ... by others we would like to make the recommendations to vaccinate twice if the dog is of a larger breed Conclusions The probability of success of rabies vaccinations of dogs depends on type of ... 120 days post vaccination The majority of dogs were also vaccinated twice, and to the best of our knowledge there is no comparative published data on the use of two doses of rabies vaccine and samples...
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Báo cáo y học: "HIV-1 prevalence and factors associated with infection in the conflict-affected region of North Uganda" pptx
Ngày tải lên :
13/08/2014, 13:21
... a great impact on the health profile of the population [2,3] The ANC of the St Mary's Hospital Lacor is located in the Gulu district of North Uganda and has participated in the national HIV-1 ... (the National Institute of Health of Italy) and AVSI, in collaboration and with the approval of the STD/AIDS Control Programme of The statistical analyses were conducted excluding data for the ... surveillance system The population living in the area comprised of the districts of Gulu, Kitgum and Pader (referred to as "Acholi region") accounts for almost half of the population living in the North-Central...
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